Take I-71 South to the Broad Street Exit (Rt. 40). Turn right on Broad Street. Go through the downtown area, past the State House, and across the Scioto River. Holy Family Church is approximately 4 blocks West of Veteran's Memorial Auditorium.
Take I-71 North to SR-315 North. Exit at Rich Street/Town Street Exit. Turn right on Rich Street (one way East). Turn left on South Gift Street. Turn left on West Broad Street. Holy Family is immediately on the right side.